This invention relates to the fraction from herbal source such as fresh green unripe fruits of Momoradica charantia (bitter gourd) using novel extraction method, which is holistic in nature, safe and devoid of any toxic solvents. The fraction prepared so is then incorporated in preparation of various the pharmaceutical dosage forms thereof to reduce blood sugar levels in patients with diabetes mellitus. 0 AJANTA HOUSE, 98, GOVT. INDUSTRIAL AREA, CHARKOP, KANDIVALI(W), MUMBAI- 400 067. AJANTA PHARMA LIMITED 768/MUM/2001 768/MUM/2001 INDIA 2009-03-25T18:07:00Z 2005-03-18 2001-08-08 417675 NIL 1) BIYANI MILIND KESHARLAL 2) BANAVALIKAR MANISHA MANOHAR 3) SUTHAR ASHISH CHANDRAKANT -2 0 76 NO NO 2005-03-18 0 1136e2CP 2009-04-30T18:55:53Z 134038 1) BIYANI MILIND KESHARLAL 2) BANAVALIKAR MANISHA MANOHAR 3) SUTHAR ASHISH CHANDRAKANT 32079 AJANTA PHARMA