METHOD FOR PRODUCING 2-CYAN-3-HYDROXY-N-(PHENYL)BUT-2-ENE AMIDES
2273/CHENP/2005 A (2273/CHENP/2005)
Filed on 2005-09-15
Publication date 2007-07-20
The invention relates to a method for obtaining cyan-3-hydroxy-N-(phenyl)but-2-ene amide, whereby a phenyl-substituted 2-cyan-N-(Phenyl)acetamide is converted in the presence of a base, acetic acid anhydride and at least one solvent, and the 2-cyan-3-hydroxy-N-(phenyl-derivative)but-2-ene amide obtained is crystallized by means of acidification.
Applicant
AVENTIS PHARMA DEUTSCHLAND GMBH
BRUNINGSTRASSE 50, D-65929 FRANKFURT AM MAIN, GERMANY Germany
Inventor
HACHTEL, JOCHEN, NEISES, BERND, SCHWAB, WILFRIED, UTZ, ROLAND, ZAHN, MARTIN
International Information
Classification
C07C 253/30
Publication number
WO 2004/083165 A1
Application date
2004-03-06
Application number
PCT/EP04/02311