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A PROCESS FOR THE PREPARATION OF AN AMIDE DERIVATIVE OF THE FORMULA Ia

3651/DELNP/2004 A (3651/DELNP/2004)

Filed on 2004-11-19

Publication date 2007-03-02

The invention concerns amide derivatives of Formula (Ia) wherein X is - NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino and carboxy; R3 is hydrogen, halogeno, (l-6C)alkyl or (I-6C)alkoxy; q is 0-4; and Q is a group such as aryl, aryloxy, aryl-(l-6C)alkoxy, arylamino and N-(l-6C)aIkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.

Applicant

ASTRAZENECA AB
S-15185 SODERTALJE, SWEDEN. Sweden

Inventor

DEARG SUTHERLAND BROWN

International Information

Classification
C07D 401/12
Publication number
WO 00/55153
Application date
2000-03-13
Application number
PCT/GB00/00912

View granted patent 225289

View application at Intellectual Property India

 
 
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