A PROCESS FOR THE PREPARATION OF AN AMIDE DERIVATIVE OF THE FORMULA Ia
3651/DELNP/2004 A (3651/DELNP/2004)
Filed on 2004-11-19
Publication date 2007-03-02
The invention concerns amide derivatives of Formula (Ia) wherein X is - NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino and carboxy; R3 is hydrogen, halogeno, (l-6C)alkyl or (I-6C)alkoxy; q is 0-4; and Q is a group such as aryl, aryloxy, aryl-(l-6C)alkoxy, arylamino and N-(l-6C)aIkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Applicant
ASTRAZENECA AB
S-15185 SODERTALJE, SWEDEN. Sweden
Inventor
DEARG SUTHERLAND BROWN
International Information
Classification
C07D 401/12
Publication number
WO 00/55153
Application date
2000-03-13
Application number
PCT/GB00/00912