SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR)
1550/DELNP/2004 A (1550/DELNP/2004)
Filed on 2004-06-04
Publication date 2007-03-02
The present invention provides the S enantiomer of a compound of formula (I); wherein R1 represents 2,4-difluo-rophenyl or cyclohexyl as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
Applicant
ASTRAZENECA AB
S-151 85 SODERTALJE, SWEDEN. Sweden
Inventor
EVA-LOTTE ALSTERMARK LINDSTEDT, ANNA CHRISTINA OLSSON, LANNA LI
International Information
Classification
C07 23520
Publication number
WO 03/051822
Application date
2002-12-18
Application number
PCT/GB02/05744