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TASTE MASKED CHEWABLE COMPOSITIONS OF SILDENAFIL CITRATE

2416/MUM/2007 A (2416/MUM/2007)

Filed on 2007-12-10

Publication date 2007-12-28

The present invention relates to chewable solid pharmaceutical composition comprising sildenafil citrate. Sildenafil citrate is a very bitter drug, hence the conventional tablets, comprise of a film coating for aesthetic appearance and acceptability. Chewable tablets are usually uncoated and hence there is a need to mask the bitter taste of sildenafil to ensure patient acceptability. The present invention achieves the taste masking of sildenafil citrate by using an ion-exchange resin which forms a complex and masks the bitter taste of sildenafil. The ion-exchange masked sildenafil complex is then incorporated with other excipients to formulate a chewable tablet using flavours and other ingredients.

Applicant

AJANTA PHARMA LTD
AJANTA HOUSE, CHARKOP, KANDIVALI (W), MUMBAI-400 067, Maharashtra India

Inventor

SINGH SHAILESH, AMIN DHANRAJ, GOUD MOHAN

International Information

Classification
C07D487/04
Publication number
NA

View application at Intellectual Property India

 
 
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