NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL
811/MUM/2004 A (811/MUM/2004)
Filed on 2004-07-30
Publication date 2007-06-22
The present invention provides an improved process for the synthesis of nebivolol or its pharmaceutically acceptable salts, more particularly hydrochloride salt of formula (l). The present invention further provides a new Form T1 of nebivolol and its pharmaceutically acceptable salts. The present invention also provides pharmaceutical composition and process for the preparation of a solid oral dosage form of nebivolol hydrochloride of formula (I), without the use of wetting agent, and optionally using binder and /or disintegrant.
Applicant
TORRENT PHARMACEUTICALS LIMITED
Torrent Research Center, P.O.Bhat-382 482,Dist.Gandhinagar, Gujarat India
Inventor
SHETH RAKESH, ATTANTI SRINIVASARAO VEERAVENKATA, PATEL HASMUKH MATHURBHAI, GUPTA VINODKUMAR, NADKARNI SUNIL SADANAND
International Information
Classification
C07D407/12 A61K31/35 A61P9/00
Publication number
NA