METHODS OF TREATING NEUROLOGICAL CONDITIONS WITH HEMATOPOEITIC GROWTH FACTORS
1419/CHENP/2005 A (1419/CHENP/2005)
Filed on 2005-06-27
Publication date 2008-08-01
ABSTRACT OF THE DISCLOSURE The present invention relates to a method of treating neurological conditions in a mammal by administering a hematopoietic growth factor such as sranulocvte-colonv stimulating factor (GCSF) and granulocyte-macrophage colonv stimulating; factor (GVlCSF)" 5 The invention also provides methods of screening for compounds that bind to a GCSF or GMCSF receptor found on the surface of a neuronal cell: and which proves a neuroprotective, nonproliferative and or a STAT gene activation activitv.
Applicant
AXARON BIOSCIENCE AG
Im Neuenheimer Feld 515, 69120 Heidelberg Germany
Inventor
SCHAEBITZ, Wolf-Ruediger, SCHNEIDER, Armin, KRUEGER, Carola, SOMMER, Clemens, SCHWAB, Stefan, KOLLMAR, Rainer, MAURER, Martin, WEBER, Daniela, GASSLER, Nikolaus
International Information
Classification
A61K38/00
Publication number
WO 2004/058287
Application date
2003-12-31
Application number
PCT/IB2003/06446