METHOD OF SYNTHESIZING KEY INTERMEDIATES FOR THE PRODUCTION OF CAMPTOTHECIN DERIVATIVES
1053/CHE/2005 A (1053/CHE/2005)
Filed on 2005-08-03
Publication date 2007-07-20
The present invention discloses a process for efficient production of 2-amino-5-hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skelton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin and novel intermediates thereof.
Applicant
AVRA LABORATORIES PVT. LTD.
AVRA HOUSE 54 SAI ENCLAVE HABSIGUDA HYDERABAD-500 007 ANDHRA PRADESH, INDIA Andhra Pradesh India
Inventor
RAO, RAMAKRISHNA, ALLA, VENKATA RAMA RAO
International Information
Classification
C07D 491/22
Publication number
NA