This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo5,6-cyclohepta1,2-bpyridine, hereinafter called 'desloratadine'. These polymorphic salt forms show much higher solubility in water and also in protic organic solvents compare to the parent desloratadine. The process of preparing the polymorphic forms comprising: a) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of from about 55°C to 70°C, and stirring for 30 to 45 minutes after mixing, and thereafter filtering the solid thereby prepared in hot condition; to yield the polymorphic form 2 having a DSC of 232°C ± 2°C; or b) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of from about 15°C to room temperature (25°C) and stirring at this temperature for 30 to 45 minutes, then filtering at room temperature; to yield the polymorphic form 1 having a DSC of 224°C ± 2°C. Lichtstrasse 35, CH-4056 Basel Switzerland SANDOZ AG 139/CHENP/2005 A 139/CHENP/2005 INDIA 2009-03-20T10:52:56Z 2007-03-30 2005-02-07 315172 2003-07-17 PCT/US2003/022312 A61K 31/4545 WO/2004/012738 RAY, Anup, Kumar, PATEL, Hiren, Kumar, V., PATEL, Mahendra R. No of Pages : 13 No of Claims : 5 6584 0 256 U.S.A. 2002-08-05 60/401, 153 2007-03-30 0 4F3Dqgf9 2009-04-30T18:40:07Z 83015 RAY, ANUP, KUMAR, PATEL, HIREN, KUMAR, V., PATEL, MAHENDRA R. NO OF PAGES : 13 NO OF CLAIMS : 5 12923 SANDOZ AG 139/CHENP/2005 10469 2008-03-28 212951 SANDOZ AG 2UziQWLa