7-ARYL-3,9-DIAZABICYCLO(3,3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
2435/CHENP/2004 A (2435/CHENP/2004)
Filed on 2004-10-27
Publication date 2008-03-28
The invention relates to novel 3,9-diazabicyclo3.3.1nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
Applicant
ACTELION PHARMACEUTICALS LTD
Gewerbestrasse 16, CH-4123 Allschwil, Switzerland
Inventor
BEZENCON, Olivier, BUR, Daniel, FISCHLI, Walter, REMEN, Lubos, RICHARD-BILDSTEIN, Sylvia, WEBER, Hans-Peter, WELLER, Thomas
International Information
Classification
C07D 471/08
Publication number
WO/2003/093267
Application date
2003-04-08
Application number
PCT/EP2003/03721