: NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS
1359/KOLNP/2003 (1359/KOLNP/2003)
Filed on 2003-10-22
Publication date 2006-03-17
Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six member saturated ring and X is C, O or S. (FIG. Nil)
Applicant
ELI LILLY AND COMPANY.
Lilly Corporate Center, Indianapolis, IN 46285 USA.
Inventor
SAWYER, Jason, Scott, BEIGHT, Douglas, Wade CIAPETTI, Paola, DECOLLO, Todd, Vincent, GODFREY, Alexander, Glenn, GOODSON, Theodore, Jr. HERRON, David, Kent, LI, Hong-Yu, LIAO, Junkai, MCMILLEN, William, Thomas, MILLER, Shawn, Christopher, MORT, Nicolas, An
International Information
Classification
C07D 487/04
Publication number
WO 02/094833
Application date
2002-05-13
Application number
PCT/US02/11884 &