PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS
1453/CHENP/2005 A (1453/CHENP/2005)
Filed on 2005-06-29
Publication date 2007-06-22
A compound of the formula (I): (1) wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, etc.; R3 is lower alkoxy, etc. ; R4 is hydroxy, etc.; X is 0, S, etc.; Y is CH or N; Z is lower alkylene or lower alkenylene; and m is 0 or 1; or salts thereof, which are useful as a medicament.
Applicant
ASTELLAS PHARMA INC
3-11, NILHONBASHI-HONCHO 2-CHOME, CHUO-KU, TOKYO 103-8411, Japan
Inventor
SHIRAI, FUMIYUKI, SHIRAI, Fumiyuki, KAYAKIRI, NATSUYA, OKUMURA, KAZUO, NAKAMURA, KATSUYA
International Information
Classification
C07D 231/12
Publication number
WO/2004/050632
Application date
2003-11-14
Application number
PCT/JP2003/014489