BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS
2719/DELNP/2004 A (2719/DELNP/2004)
Filed on 2004-09-15
Publication date 2007-03-02
The invention concerns a compound of the formula (I) wherein Ring A is heterocyclyl; m is 0-4 and each R1 is a group such as hydroxy, halo, trifluoromethyl and cyano; R2 is halo and n is 0-2; and each R4 is a group such as hydroxy, halo, trifluoromethyi and cyano; p is (M; and R3 is amino or hydroxy; or pharmaceutically-acceptaWe salts or in-vivo-hydrolysable ester or amide thereof processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by histone deacetylase.
Applicant
ASTRAZENECA AB
S-151 85 SöDERTäLJE, SWEDEN Sweden
Inventor
ELAINE SOPHIE ELIZABETH STOKES, CRAIG ANTHONY ROBERTS, MICHAEL JAMES WARING
International Information
Classification
C07D 213/56
Publication number
WO 03/087057
Application date
2003-04-02
Application number
PCT/GB03/01442