"COMPOSITIONS FOR TREATMENT OF SYSTEMIC MASTOCYTOSIS"
Application 691/DELNP/2008 published 2008-07-11, filed 2008-01-24
COMPOSITIONS FOR TREATMENT OF SYSTEMIC MASTOCYTOSIS The present invention relates to the use of the combination of tyrosine phosphate inhibitors AMN107 and PKC412 for the preparation of a drug for the treatment of a mast cell-related proliferate disease. The present invention is also drawn to a combination treatment of a tyrosine phosphate inhibitor and a TK-inhibitor that is effective against a mast cell-related proliferative disease, including especially systemic mastocytosis (SM) including aggressive SM (ASM) and mast cell leukemia (MCL). No. of Pages : 78 No. of Claims : 36
Applicant
1)VALENT PETER
:MEDICAL UNIVERSITY OF VIENNA, DEPARTMENT OF INTERNAL MEDICINE,1,DIVISION OF HEMATOLOGY & HEMOSTASEOLOGY, AKH-WIEN WAEHRINGER GUERTEL 18-20,A-1097 VIENNA AUSTRIA. Austria
Inventor
1)VALENT PETER
International Info
Classification: A61K 45/06
Publication Number: WO 2007/010014
Application Date: 2006-07-19
Priority Information
60/701,098 U.S.A. 2005-07-20