"OPTIMIZED ANTI-CD30 ANTIBODIES"
Application 2873/DELNP/2008 published 2008-07-25, filed 2008-04-07
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody. No. of Pages : 132 No. of Claims : 22
Applicant
1)XENCOR, INC.
:111 WEST LEMON AVENUE, MONROVIA, CALIFORNIA 91016, U.S.A U.S.A.
Inventor
1)LAZAR, GREGORY, ALAN 2)DESJARLAIS, JOHN, R 3)HAMMOND, PHILIP, W 4)CARMICHAEL, DAVID F 5)CHEN, BAO-LI 6)CHU, SEUNG, Y 7)KARKI, SHER, BAHADUR 8)KUNKEL, LORI
International Info
Classification: C07K 16/28
Publication Number: WO 2007/044616
Application Date: 2006-10-06
Priority Information
60/724,624 U.S.A. 2005-10-06