"CAMPTOTHECIN DERIVATIVES AS CHEMORADIOSENSITIZING AGENTS"
Application 4329/DELNP/2008 published 2008-08-15, filed 2008-05-21
Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy. No. of Pages : 134 No. of Claims : 57
Applicant
1)CALIFORNIA PACIFIC MEDICAL CENTER
:475 BRANAN STREET, SUITE 220, SAN FRANCISCO, CALIFORNIA 94107-1739 USA. U.S.A. 2)CATHOLIC HEALTHCARE WEST
Inventor
1)YANG LI-XI
International Info
Classification: A61K 31/44
Publication Number: WO 2007/048002
Application Date: 2006-10-19
Priority Information
60/728,924 U.S.A. 2005-10-21