MEDICINAL COMPOSTIONS FOR IMPROVING ORAL ABSORPTION
Application 982/KOLNP/2004 published 2005-12-30, filed 2004-07-13
Inhibitors for degradation of a physiologically active peptide with a digestive enzyme which comprise an aminoalkyl methacrylate copolymer E as the active ingredient; viscosity-lowering agents for a digestive tract mucosa and/or mucus layers distributed thereon which comprise aminoalkyl methacrylate copolymers E as the active ingredient; and medicinal compositions for improving oral absorption which contain a physiologically active peptide and an aminoalkyl methacrylate copolymer E. These medicinal compositions make it possible to achieve an excellent oral absorbability of a physiologically active peptide which has been considered as hardly absorbable orally. (FIG. - nil)
Applicant
YAMANOUCHI PHARMACEUTICAL CO.LTD.
3-11 NOHONBASHI-HONCHO,2-CHOME,CHUO-KU,TOKYO 103-8411 JAPAN
Inventor
1. SHUNSUKE WATANABE 2. KIYO NAKANISHI 3. SHIGEO TAKEMURA 4. YUUKI TSUTSUI
International Info
Classification: A1K 47/30,47/46,38/22,A61P 43/00
Publication Number: WO 03/059389 A1
Application Date: 2003-01-15
Priority Information
60/349,784 US 2002-01-16