METABOLITES OF 2-{3-[4-
Application 464/DEL/2005 published 2006-11-10, filed 2005-03-02
The present invention relates to the metabolites of 2-{3-[4-(2-isopoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a-tetrahydro-1h-isoindole-1,3(2H)-dione of formula 1. The disclosed compounds can function as alpha1a-adrenoceptor antagonists and thus can be used for the treatment of benign prostatic hyperplasia (BPH) and related symptoms thereof. Processes for preparing the meatabolites, pharmaceutical composition containing these metabolites and the method of treating BPH and related symptoms thereof are also provided.
Applicant
1)RANBAXY LABORATORIES LIMITED
:19, NEHRU PLACE, NEW DELHI-110019, INDIA Delhi India
Inventor
1)NITYA ANAND 2)MOHAMMAD SALMAN 3)GYAN CHAND YADAV 4)SOMESH SHARMA 5)SANJAY JAIN 6)NEELIMA SINHA 7)GOBIND SINGH KAPKOTI 8)ANITA CHUGH 9)BRIJESH VARSHNEY 10)JYOTI KUMAR PALIWAL 11)KAMNA NANDA 12)SONALI KAKAR
International Info
Classification: C07D401/06