BigPatents India

A small interfering ribonucleic acid (siRNA) for inhibiting the expression of a protein encoded by SEQ ID 17 or an isoforn thereof in a cell and polypeptide comprising SEQ ID 18, wherein the siRNA comprises at least 2 sequences that are complementary to each other and wherein a sense strand comprises a first sequence and an anti-sense strand comprises a second sequence comprising a region of complementary, which is substantially complementary to at least a part of mRNA encoding a nucleotide sequence from SEQ ID 17, wherein the said siRNA upon contact with a cell expressing protein encoded by SEQ ID 17 or an isoform thereof or expression of polypeptide comprising SEQ ID 18 in a cell.