: PREPARATION METHIOD OF VALIENAMINE FROM ACARBOSE AND/OR ACARBOSE DERIVATIVES USING TRIFLUOROACETIC ACID
Application 1947/KOLNP/2004 published 2005-12-30, filed 2004-12-17
The present invention relates to a preparation method of valienamine from acarbose and/or acarbose derivatives using organic acid TFA(trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a VWURQJUHWDUGDQWRI.-glucosidase and which is used for the cure of diabetes, can be produced in large quantities by using selective hydrolysis from acarbose and/or acarbose derivatives using TFA. (FIG. NIL)
Applicant
B T GIN INC
306 SANHAKHYUPLYUKKWAN,JOONGBU UNIVERSITY,SAN 2-25,MAJEON-RI,CHUBU-MYEON,GEUMSAN-GUN,CHUNGCHEONGNAM-DO,312-702,REPUBLIC OF KOREA
Inventor
1. HER YOUL 2. OH JIN-HWAN
International Info
Classification: C07C 209/62
Publication Number: WO 04/000782 A1
Application Date: 2002-11-23
Priority Information
2002-35683 KR 2002-06-25