PEG-CONJUGATES OF HGT-NK4
Application 1310/CHENP/2003 published 2005-11-25, filed 2003-08-21
A conjugate comprising an N-terminal fragment of hepatocyte growth factor (HGF/SF) consisting of the hairpin domain and the four kringle regions of the a-chain and a polyethylene glycol group having an overall molecular weight of from about 20 to 40 kDA, has improved properties is a useful therapeutic agent for tumor treatment
Applicant
F. HOFFMANN-LA ROCHE AG
124 Grenzacharstrasse, CH-4070 Basle SWITZERLAND
Inventor
International Info
Classification: A61K 47/48
Publication Number:
Priority Information
01104640.6 EUROPE 2001-02-23