PHARMACEUTICAL DOSAGE FORM OF AMORPHOUS NELFINAVIR MESYLATE

Application 1705/CHENP/2003 published 2005-11-18, filed 2003-10-28
A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate, and a pharmaceutically acceptable, water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, said copolymer having a melting point of at least 40 C. A hot melt granulation process for making the dosage form is provided.

Applicant

F. HOFFMANN-LA ROCHE AG
124 Grenzacharstrasse, CH-4070 Basel Switzerland

Inventor

International Info

Classification: A61K 38/55, 9/20, A61P 31/12, 31/18
Publication Number: PCT/EP02/04711

Priority Information

60/288,410 USA 2001-05-03