CD20 BINDING MOLECULES
Application 2488/KOLNP/2005 published 2006-10-13, filed 2005-12-05
The present invention relates to CD20 binding molecules and nucleic acid sequences encoding CD20 binding molecules. In particular, the present invention relates to CD20 binding molecules with a high binding affinity, and a low dissociation rate, with regard to human CD20. Preferably, the CD20 binding molecules of the present invention comprise light and/or heavy chain variable regions with fully human frameworks (e.g. human germline frameworks). (FIG. - nil)
Applicant
APPLIED MOLECULAR EVOLUTION
3520 DUNHILL STREET, SAN DIEGO CA 92121 USA
Inventor
1. JEFFRY DEAN WATKINS 2. JULIAN DAVIES 3. DAVID MATTHEW MARQUIS 4. BARRETT W ALLAN 5. BRAIN ONDEK
International Info
Classification: A61K 39/395,C07K 16/28,16/30
Publication Number: WO 04/103404 A1
Application Date: 2004-05-20
Priority Information
60/471,958 US 2003-05-20