IMPLANTABLE ELASTOMERIC DEPOT COMPOSITIONS, USES THEREOF AND METHOD OF MANUFACTURING

Application 2491/KOLNP/2005 published 2006-10-13, filed 2005-12-06
Methods and compositions for systemically or locally administering a beneficial agent to a subject are described, and include, for example, implantable elastomeric depot compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a prolonged duration of time. The compositions include a biocompatible, elastomeric polymer, a biocompatible solvent having low water miscibility that forms an elastomeric viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent. (FIG. 1)

Applicant

ALZA CORPORATION
1900, CHARLESTON ROAD, P.O.BOX 7210, MOUNTAIN VIEW, CA 94039-7210, USA.

Inventor

CHEN, GUOHUA HOUSTON, PAUL KLEINER, LOTHAR NATHAN, ARUNA ROSENBLATT, JOEL

International Info

Classification: A61K 9/00
Publication Number: WO 04/108111
Application Date: 2004-05-28

Priority Information

60/474,874 US 2003-05-30