BigPatents India

The present inventions relates to a process for extraction of active compounds from Picrasma quassioides-(D. Don.) of family Simaroubaceae. The plant grows at an altitude of 3000 feet from sea level in hilly terrain of North East India. In general Heartwod is pale green to yellow with dark streaks, while the sapwood is wide and cream colour. It is ring-porous with wide rays, superficially resembling ash. Young branches red-brown with yellow spots. Leaves alternate, odd-pinnate, petioles 2-4 cm long; leaflets 7-9, sessile, ovate or Narrowly ovate,.4-10 cm long, 1.5-3 cm wide, acuminate with obtuse tip. Flowers yellowish green, 4-7 mm. across; sepals 4-5, ovate; petals 4-5, obovate, 3-4 mm long.Fruits 5 drupelets(berry), globose-obovoid,6- 7 mm in diameter, red in colour. Bitter in taste due to the presence of alkaloids. The object of the present inventions is to provide a process for the extraction of the active compounds their identification and characterization using various analytical tools from the herbal plant. A further object of this invention is to provide a simple extractive process using a chip yet commonly available material widely available in India. A still further object of the present invention is to evolve a process for the recovery of active chemical compounds at a considerably fast rate, thereby reducing the contact time and saving wastage of material. Yet another object of this invention is to provide an extractive process of for extraction of the active compounds their identification and characterization and recovery of wherein the quantum of recovery is near total (99%). The extractive process evolved for the first time by the applicant has resulted in recovery of extremely useful active compounds which has been used among human population (Volunteer) with response of recovery from various ailments like fever, loss of appetite, gastrointestinal disorder and weakness. The survey on 1000 human population with success rate of median value of 52%. The solid mass was dissolved in methanol and injected in Gas Chromatography Instrument and the following compounds were identified and further confirmed by NMR., elemental analyses. Caryophyllene oxide; Longifolenaldehyde; Diepi-alpha-cedrene epoxide; Tricyclo [5, 2, 2.0( l.6)undecan-3-ol.2-melhylene-6,8,8-trimethyl; Alloaromadendrene oxide-(l); Isoarodendrene epoxide; Calarene epoxide; Diepicedreiie-l -oxide; 9-lsopropyl-l-methyl-2methylene-5-oxatricyclo{5.4.0.0(3.8) und; 6-{Isopropenyl 1-4, 8a-dimethyl-l,2,3,5,6,7,8,8a-octahydro-naphthal. It is to be noted the invention described above is by way of illustration and the invention is not to be restricted to the data given as it includes within its ambit the obvious modification and equivalents as would be apparent to a person skilled in the art. A process for extraction of active compounds from Picrasma quassioides-(D. Don.) of family Simaroubaceae and identification of the same thereof, substantially as herein described. The active compounds from Picrasma quassioidcs-(D. Don.) of family Simaroubaceae. Substantially as herein described.