IMMUNOSTIMULATORY G,U-CONTAINING OLIGORIBONUCLEOTIDES
Application 1467/KOLNP/2004 published 2006-11-24, filed 2004-10-04
Compositions and methods relating to immunostimulatory RNA oligomers are provided. The immunostimulatory RNA molecules are believed to represent natural ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). The compositions and methods are useful for stimulating immune activation. Methods useful for screening candidate immunostimulatory compounds are also provided. (FIGnil.)
Applicant
COLEY PHARMACEUTICAL GMBH
ELISABETH-SELBERT-STRASSE9, 40764 LANGENFELD, GERMANY
Inventor
LIPFORD GRAYSON B; NAUER STEFAN; WAGNER HERMANN
International Info
Classification: A61K
Publication Number: WO 03/086280
Application Date: 2003-04-04
Priority Information
60/370515 USA 2002-04-04
60/421966 USA 2002-10-29