EPIMERIZED DERIVATIVES OF K5 POLYSACCHARIDE WITH A VERY HIGH DEGREE OF SULFATION
Application 1963/KOLNP/2004 published 2006-11-24, filed 2004-12-20
A new method is described for the oversulfation of epiK5-N-sulfate to obtain an epiK5-amine-O-oversulfate with very high sulfation degree which, by subsequent N-sulfation, provides new epiK5-N,O-oversulfate-derivatives with a sulfation degree of at least 4, basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field. Also described are new low molecular weight epiK5-N-sulfates useful as intermediates in the preparation of the corresponding LMW-epiK5-N,O-oversulfate-derivatives. (FIG. - Nil)
Applicant
GLYCORES 2000 S.R.L
VIA MAC MAHON 43, I-20155 MILAN ITALY
Inventor
1.ORESTE PAQUA ANNA 2.ZOPPETTI GIORGIO
International Info
Classification: C08B 37/00,37/08,37/10,A61K 31/726,31/727,31/737
Publication Number: WO 03/106504 A1
Application Date: 2003-06-17
Priority Information
MI2002A001345 IT 2002-06-18