" THIAZOLE-DERIVATIVES"

Application IN/PCT/2001/543/CHE published 2005-03-04, filed 2001-04-17
Compounds of formula (I) as well as pharmaceutically usable suits and esters thereof, wherein R1, R2 and R3 have the significance given in claim 1, inhibit the binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the farm of pharmaceutical preparations in the control or prevention of neoplasms, Tumour metastasizing, tumour growth, osteoporosis, Paget’s disease, diabetic retinopathy, macular degeneration, restenosis Following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure as well as infections caused by viruses, bacteria or fungi.

Applicant

F. HOFFMANN-LA ROCHE AG,
of 124 Grenzacherstrasse, CH-4070 Basel,, a swiss company,, SWITZERLAND

Inventor

International Info

Classification: C 07D 277/48, A61K 31/427
Publication Number: EP99/07824

Priority Information

98119985.4 EUROPEAN 1998-10-22