"4-
Application IN/PCT/2001/974/CHE published 2005-03-04, filed 2001-07-10
The compounds of formula (I) wherein R1, R2 and X have the significance as given in the description, are inhibitors of endothelin receptors and can therefore be used for the treatment of disorders which are associated with abnormal vascular tone an endothelial dysfunction.
Applicant
F HOFFMANN-LA ROCHE AG,
of 124 Grenacherstrasse,, CH-4070 Basel,, Switzerland,, a Swiss Company.
Inventor
International Info
Classification: C07D 401/12, A61K 31/505, A61P 9/00
Publication Number: PCT/EP00/00103
Priority Information
99100784.0 EP 1999-01-18