"PHENYLALANINOL DERIVATIVES"
Application IN/PCT/2001/1103/CHE published 2005-03-04, filed 2001-08-03
Compounds of formula (1) and the pharmaceutically acceptable salts and esters thereof wherein X and Y are as defined in the specification, are effective inhibitors of the binding of VCAM-1 to VLA-4 in vivo and are useful in treating inflammation in inflammatory diseases in which such binding such binding acts to bring on the inflammation.
Applicant
F HOFFMANN-LA ROCHE AG
of 124 Grenzacherstrasse,, CH-4070 Basle,, a Swiss Company, Switzerland.
Inventor
International Info
Classification: C07C 233/80, 235/40, 317/44, 323/60, A61K 31/167 & A61P 29/00
Publication Number: PCT/EP00/01168
Priority Information
60/120,498 US 2000-02-18