BigPatents India

"Cyanopyrrolidine derivatives represented by the general formula (1) or pharmaceutically acceptable salts thereof: (1) wherein R1 is halogeno, hydroxyl, or the like, and R2 is hydrogen, halogeno, or the like, or alternatively R1 and R2 are united to form oxo, hydroxyimino, or the like; R3 and R4 are each hydrogen, halogeno, or the like, or alternatively R3 and R4 are united to form oxo, hydroxyimino, or the like; X is oxygen or sulfur; Y is CR5R6- (wherein R5 and R6 are each independently hydrogen, halogeno, or the like) or CR7R8-CR9R10- (wherein R7, R8, R9, and R10 are each independently hydrogen, halogeno, or the like, or alternatively R7 and R9 together with the carbon atoms adjacent thereto form C3-8 cycloalkyl or the like); and Z is hydrogen, C1-10 alkyl,or the like, or alternatively Y and Z together with the nitrogen atom adjacent thereto form cyclic C2-10 amino or the like."