"GLOBAL ANALYSIS OF PROTEIN ACTIVITIES USING PROTEOME CHIPS"

Application 1954/CHENP/2003 published 2006-01-06, filed 2003-12-09
The present invention relates to proteome chips comprising arrays having a large proportion of all proteins expressed in a single species. The invention also relates to methods for making proteome chips. The invention also relates to methods for using proteome chips to systematically assay all protein interactions in a species in a high-throughput manner. The present invention also relates to methods for making and purifying eukaryotic proteins in a high-density array format. The invention also relates to methods for making protein arrays by attaching double-tagged fusion proteins to a solid support. The invention also relates to a method for identifying whether a signal is positive.

Applicant

YALE UNIVERSITY
Two Whitney Avenue, New Haven, CT 06511, USA.

Inventor

International Info

Classification: A61K 38/00
Publication Number: PCT/US02/14982

Priority Information

60/290,583 USA 2001-05-11
60/308,149 USA 2001-07-26