AN IMPROVED PROCESS FOR THE PREPARATION OF LEFLUNOMIDE
Application 98/MUM/2002 published 2006-01-06, filed 2002-02-04
The present invention discloses a process for the preparation of leflunomide by the condensation of 4-(trifluoromethyl) aniline(1) and 5-methylisoxazole-4-carboxylic acid chloride (2) in such a novel manner to give leflunomide of high purity and in good yield. Drawing : NIL Total Pages: 6
Applicant
ALEMBIC LIMITED
ALEMBIC ROAD, VADODARA-390 003, GUJARAT, INDIA
Inventor
1. SANKAR ADHIKARI 2. ALOK S. MEHTA 3. SRINIVASAN RENGARAJU
International Info
Classification: A61K 31/42