ALTERED STRAIN OF THE MODIFIED VACCINIA VIRUS ANKARA
Application 1007/MUMNP/2005 published 2006-05-12, filed 2005-09-13
The invention provides new strains of the Modified Vaccinia Virus Ankara (MVA) that have a strongly reduced virulence for most mammals, especially humans, but nevertheless grows in cells of a continuous cell line approved for the production of a therapeutic agent such as a vaccine. The invention also provides a method for producing said adapted MVA strains. The adapted MVA can be used e.g. for parenteral immunization, as a vector system, or in the active or inactivated from as an adjuvant or as a regulator of the unspecific components of the immune system. Drawing: 09 Sheets. Total Pages: 37
Applicant
BAVARIAN NORDIC A/S
BOEGESKOVVEJ 9, DK-3490 K VISTGAARD, DENMARK.
Inventor
ANTON MAYR
International Info
Classification: C12N 7/08, 15/863, A61K 39/275, 39/39, 48/00, 35/76, A61P 31/20
Publication Number: WO 01/68820
Application Date: 2001-03-10
Priority Information
PA200000410 DENMARK 2000-03-14