METHOD OF MEASURING CARDIAC RELATED PARAMETERS NON-INVASIVELY VIA THE LUNG DURING SPONTANEOUS AND CONTROLLED VENTILATION
Application 1027/MUMNP/2005 published 2006-05-12, filed 2005-09-16
An apparatus to measure cardiac output (Q) and other parameters such as alveolar ventilation (VA), minute CO2 elimination from the lung (VCO2), minute oxygen consumption (VO2), oxygenated mixed venous partial pressure of CO2, (PvCO2-oxy), true mixed venous partial pressure of CO2 (Pv CO2), PaCO2, mixed venous oxygen saturation (SvO2), pulmonary shunt, and anatomical dead space, consisting of: a) a breathing circuit with characteristics that: i. on exhalation, exhaled gas is kept substantially separate from inhaled gas; ii. oninhalation, when VE is greater than FGS flow, the subject inhales FGS first and then inhales a gas that is substantially SGS, for the balance of inhalation; b) gas sensor means for monitoring gas concentrations at the patient-circuit interface c) a first gas set (FGS), and a second gas set (SGS), said second gas set which may comprise previously exhaled gases or exogenous gases or both d) a gas flow control means for controlling the rate of FGS flow into the breathing circuit e) means to identify phase of breathing, said means may consist of pressure sensors or analysis of signal generated by gas sensors or other means known to those skilled in the art; f) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means, receiving the output of the gas sensor means and means to identify phased of breathing, and performing the calculations for measuring cardiac output and other parameters as outlined in the disclosure. Drawing 21 Sheets. Total Pages: 88 (FIG.- 6A)
Applicant
1. FISHER JOSEPH 2. PREISS DAVID 3. AZAMI TAKAFUMI 4. VESELY ALEX 5. PRISMAN ELTAN 6. ISCOE STEVE 7. SOMOGYI RON
C/O THE TORONTO GENERAL HOSPITAL, DEPARTMENT OF ANESTHESIA, 200 ELIZABETH STREET, TORONTO, ONTARIO M5G 2C4, CANADA.
Inventor
1. FISHER JOSEPH 2. PREISS DAVID 3. AZAMI TAKAFUMI 4. VESELY ALEX 5. PRISMAN ELTAN 6. ISCOE STEVE 7. SOMOGYI RON
International Info
Classification: A61B 5/083, 5/08, A61M 16/00
Publication Number: WO 2004/073482
Application Date: 2004-02-18
Priority Information
2,419,622 CANADA 2003-02-19