CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES
Application 498/KOLNP/2004 published 2006-06-02, filed 2004-04-16
This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions, and methods of using these compounds for such treatment. (FIG. NIL)
Applicant
CORTEX PHARMACEUTICALS INC
15241 BARRANCA PARKWAY IRVIONE CA 92618 USA
Inventor
1. ROGERS GARY A 2. ALLAN MATTHEW 3. HARRIS CLAYTON 4. HUNG JIANJIE 5. MARRS CHRISTOPHER M 6. MUELLER RUDOLF 7. RACHWAL STANISLAW
International Info
Classification: C07D 265/24,491/04,498/04,513/04,515/04 A61K 31/536,31/5365,A61P 25/18
Publication Number: WO 03/045315 A3
Application Date: 2002-11-25
Priority Information
60/333,334 US 1920-11-26