MODIFIED RELEASE COMPOSITION COMPRISING A SHORT-ACTING HYPNOTIC FOR TREATMENT OF SLEEP DISORDERS
Application 1155/KOLNP/2005 published 2006-07-07, filed 2005-06-15
A pharmaceutical composition comprising a first component comprising a short-acting hypnotic or a pharmaceutically acceptable salt thereof; a second component comprising at least one particle, wherein the at least one particle comprises a core and at least one coating over the core, the core comprising a short-acting hypnotic or a pharmaceutically acceptable salt thereof, and the at least one coating comprising at least one pharmaceutically acceptable polymer that is soluble at a pH greater than or equal to about 5.5, and optionally a third component comprising at least one particle, wherein the at least one particle comprises a core and at least one coating over the core, the core comprising a short-acting hypnotic or a pharmaceutically acceptable salt thereof, and the at least one coating comprising at least one pharmaceutically acceptable polymer that is soluble at a pH greater than or equal to about 6.0. Methods of treating sleep disorders, prolonging sleep, and inducing sleep using these compositions are also disclosed (FIG. nil)
Applicant
ELAN PHARMACEUTICALS, INC.,
800 GATEWAY BOULEVARD, SOUTH SAN FRANCISCO, CA 94080, USA.
Inventor
CODD JANET WILSON ALISON CLANCY MAURICE O’HANLON MELANIE
International Info
Classification: A61K 9/52, 9/22, 31/519, A61P 25/20
Publication Number: WO 04/045589
Application Date: 2003-11-14
Priority Information
60/426,369 US 2002-11-15
10/704,633 US 2003-11-12