ANTI-AB ANTIBODIES AND THEIR USE.

Application 1841/CHENP/2004 published 2006-06-23, filed 2004-08-18
The present invention relates to antibody molecules capable of specifically recognizing two regions of the R-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a fragment thereof. Furthermore, nucleic acid molecules encoding the inventive antibody molecules and vectors and hosts comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions, preferably pharmaceutical or diagnostic compositions, comprising the compounds of the invention as well as for specific uses of the antibody molecules, nucleic acid molecules, vectors or hosts of the invention.

Applicant

F. HOFFMANN-LA ROCHE AG . MORPHOSYS AG .
Grenzacherstrasse 124, CH-4070 Basel ,, Lena-Christ-Strasse 48, 82152 Martinsried ,, SWITZERLAND . GERMANY .

Inventor

International Info

Classification: A61K 39/00
Publication Number: PCT/EP2003/001759

Priority Information

02003844.4 EUROPE. 2002-02-20