BigPatents India

A process for the preparation of gabapentin form-li comprising steps:-Reaction of 1,1-cyclohexane diacetic acid mono amide with alkali hypo halite solution, acidification with acid(s) in presence of solvent(s) Extraction of the formed gabapentin acid salt(s) into organic layer -Separation of the organic layer, drying over dehydrating agents Addition of ante solvent(s), followed by optional cooling to precipitate the gabapentin acid salt(s) and its isolation -Dissolution of gabapentin acid salts in short chain alcohol -pH adjustment of the solution with base(s) in a specified temperature range -Cooling the reaction mass to precipitate gabapentin form -IV -Separatior of the formed gabapentin form-IV -Conversion of the form-IV into form-il by slurring in ethanol in a specified temperature range -Separation of gabapentin form-II followed by drying A process as claimed in claim 1 wherein acidification is done with?