METHOD FOR THE IDENTIFICATION OF LIGANDS
Application 1972/KOLNP/2004 published 2006-07-14, filed 2004-12-21
The present invention relates generally to a method of identifying ligands that modulate protein-protein interactions. More particularly, the present invention relates to methods of determining agonists or antagonists of a co-regulator dependent target molecule based on the ability to modify the stability of the target molecule. (FIG. nil)
Applicant
3-DIMENSIONAL PHARMACEUTICALS, INC.
EAGLEVIEW CORPORATE CENTER, 665 STOCKTON DRIVE, SUITE 104, EXTON, PA 19341, UNITED STATES OF AMERICA
Inventor
RENTZEPERIS, Dionisios; ASKARI, Hossein; SPRINGER, Barry, A.; BONE, Roger, F.; SALEMME, Francis, R.
International Info
Classification: G01N 33/53, A61K 38/00, 2/00
Publication Number: WO 2004/010141
Application Date: 2002-09-20
Priority Information
60/398,023 USA 2002-07-24