A COST EFFECTIVE PROCESS FOR PREPARATION FOR MANUFACTURE OF IRON SUCROSE

Application 1298/MUM/2004 published 2006-07-21, filed 2004-12-06
A process of preparing iron sucrose complex, comprising the steps of : a) reacting a ferric salt with a base in a solvent, at a selected pH range and isolating ferric oxyhydroxide, b) reacting sucrose and ferric oxyhydroxide in an aqueous medium comprising of sodium ions, with gradual adjustment of pH at selected temperature, and c) isolating iron sucrose complex from the reaction mixture by concentrating the reaction mixture and adding to an organic solvent or reversely adding the organic solvent to the concentrated reaction mixture and filtering. Drawing Sheets: NIL Total Pages: 23. Fig. Nil

Applicant

EMCURE PHARMACEUTICALS LIMITED
R&D CENTRE II, 12/2 F-II BLOCK, M.I.D.C. PIMPRI, PUNE-411018, MAHARASHTRA, INDIA.

Inventor

DR.MILIND MORESHWAR GHARPURE DR.BABURAO MANIKRAO BHAWAL DR.RAJIV PANDURANG SUTAR DR.SATISH RAMANLAL MEHTA

International Info

Classification: C07H 23/00, A61K 31/7135, A61P 7/06