AN IMPROVED PROCESS FOR PRODUCTION OF INTERMEDIATE OF ANTIDEPRESSANT AGENT
Application 1396/MUM/2004 published 2006-07-21, filed 2004-12-22
The present invention discloses a process for the preparation of substituted aryl alkylamine compounds comprising the steps of, reducing the substituted aryl acetonitrile substrate using Raney nickel catalyst at lower substrate/catalyst ratio of 20:1 to 6:1 with higher substrate concentration, at ramped temperature/pressure profile, in the presence of an alcoholic solvent selected from C1 to C4 alcohol and isolating the corresponding substituted phenyl ethylamine as a suitable salt. Drawing NIL Sheets. Total Pages: 21. Fig. Nil
Applicant
CALYX CHEMICALS & PHARMACEUTICALS PRIVATE LIMITED
5, MARWAH’S COMPLEX, SAKIVIHAR ROAD, SAKINAKA, ANDHERI
Inventor
1. NARAYANAIYER VISWANATHAN 2. CHATURVEDI ROHIT 3. SAJIKUMARI BAIJU 4. T-PYATI RAGHAVENDRA SHIVALING 5. YADAV SURENDRA KUMAR 6. YADAV PRASHANT KUNDLIK
International Info
Classification: C07C 87/28