BigPatents India

A pharmaceutical gastro-retentive delivery system for controlled release of therapeutically active agent in stomach or upper part of gastro-intestinal tract in the form of bilayer dosage form which comprises, One layer (layer-A) which is responsible for retaining the dosage form in stomach or upper part of gastro-intestinal tract (spatial control) for a prolonged period, comprising of pharmaceutical excipients having low bulk desity, optionally with other pharmaceutical aids. Second layer (Layer-B) which is responsible for prolonged or controlled drug delivery (temporal control) of therapeutic agent which comprises of the active agent and controlled release matrix polymers optionally with other pharmaceutical aids. Drawing Sheets: NIL Total Pages: 20. Fig. Nil