2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL

Application 1189/KOLNP/2005 published 2006-06-09, filed 2005-06-21
Compounds having formula I are provided where the variables have the values described herein. (I). Pharmaceutical formulations include the compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and combinations with other agents. A method of treating a patient comprises administering a pharmaceutical formulation according to the invention to a patient in need thereof. (FIG). Nil

Applicant

CHIRON CORPORATION.,
4-38 MINATO-MACHI, 1-CHOME, NANIWA-KU, OSAKA-SHI, OSAKA 556-0017, JAPAN.4560 HORTON STREET, EMERYVILLE, CA 94608-2916, USA.

Inventor

1) NUSS, JOHN, M. 2) PECCHI, SABINA 3) RENHOWE, PAUL, A

International Info

Classification: C07D 401/12, 407/14, 403/12, 407/12, 239/48, 417/12, 403/04, 403/14, 401/14, A61K 31/506, A61P 35/00
Publication Number: WO 04/048365
Application Date: 2003-11-21

Priority Information

60/428,473 US 2002-11-21
60/438,568 US 2003-01-07
60/523,081 US 2003-11-19