CRYSTAL MODIFICATION OF 5-SUBSTITUTED-2-OXAZOLIDONE DERIVATIVE AND ITS PROCESS THEREOF
Application 71/MUM/2005 published 2006-08-11, filed 2005-01-24
The present invention discloses crystalline polymorphic Form 1 of compound 5-(3,5-dimethylphenoxy-)methyl)-2-oxazolidinone, characterized by x-ray diffraction pattern having peaks at 10.355, 14.285, 18.625, 19.030, 20.810 and 22.475 0.30 degrees 2 theta angle, and melting point ranging from 122.5C to 124C which is characterized by Differential Scanning Calorimetry. The present invention further discloses processes for the preparation thereof, pharmaceutical preparation comprising the said polymorph and its use in the treatment of depression central synaptic transmissions. Drawing: 04 Sheets. Total Pages: 24. Fig. Nil
Applicant
FDC LIMITED
B-8 MIDC INDUSTRIAL ESTATE WALUJ-431136, MAHARASHTRA, INDIA.
Inventor
1. MOHAN ANAND CHANDAVARKAR 2. UDAY RAJARAM BAPAT 3. VIVEK MANOHAR KHARE
International Info
Classification: C07D 263/24