A PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATE AND ITS CONVERSION TO VENLAFAXINE

Application 82/MUM/2005 published 2006-08-11, filed 2005-01-27
A process for the preparation of the compound of formula (I), namely 2-(4-methoxy-phenyl)-1-oxa-spiro [2.5] octane-2-carbonitrile in which the compound corresponding to formula (II), namely (1-bromo-cyclohexyl)-(4-methoxy-phenyl)-methanone, is subjected to treatment with a cyanation agent. Wherein compound of formula (II) is prepared by subjecting the compound corresponding to formula (III): Namely cyclohexyl-(4-methoxy-phenyl)-PHWKDQRQHWRWUHDWPHQWZLWKDQ.–keto-halogenating agent. Drawing Sheets: NIL Total Pages: 38. Fig. Nil

Applicant

ALEMBIC LIMITED
ALEMBIC ROAD, VADODARA-390003, GUJARAT, INDIA.

Inventor

1. RATHOD DHIRAJ MOHANSINH 2. SRINIVASAN RENGARAJU 3. GHARPURE MILIND MORESHWAR 4. PATEL NISHANT MAHENDRA 5. DEOAHAR MANDAR MANOHAR

International Info

Classification: C07C 217/74, C07C 253/04, C07C 253/16