. STROMAL CELL-DERIVED FACTOR –1 MEDIATES STEM CELL HOMING AND TISSUE REGENERATION IN ISCHEMIC CARDIOMYOPATHY
Application 615/DELNP/2005 published 2006-06-09, filed 2005-02-17
method of treating infarcted myocardial tissue includes, the concentration of SDF-1 protein in the infarcted tissue. The concentration of stem cells in the peripheral blood of the infarcted tissue is also increased. The number of stem cells in the peripheral blood is increased while the concentration of SDF-1 in the infarcted tissue is increased.
Applicant
THE CLEVELAND CLINIC FOUNDATION
9500 EUCLID AVENUE, CLEVELAND, OH 44122, USA
Inventor
: PENN, MARC S ASKARI ARMAN T KIEDROWSKI MATTHEW : NO
International Info
Classification: A61K 31/70
Publication Number: WO 2004/017978
Application Date: 2003-08-21
Priority Information
60/405,274 US 2002-08-22
60/426,712 US 2003-04-30