RECOMBINANT CARRIER MOLECULE FOR EXPRESSION, DELIVERY AND PURIFICATION OF TARGET POLYPEPTIDES
Application 2639/KOLNP/2005 published 2006-10-20, filed 2005-12-20
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B (Lic B) were also made and used it as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest. (FIG. Nil)
Applicant
FRAUNHOFER USA, INC.,
46025 PORT STREET, PLYMOUTH MI 48170, USA.
Inventor
YUSIBOV, VIDADI METT, VADIM MUSIYSCHUK, KONSTANTIN PIRUZIAN, ELEONORA GOLDENKOVA, IRINA
International Info
Classification: C12Q
Publication Number: WO 05/026375
Application Date: 2004-05-24
Priority Information
60/472,495 US 2003-05-22