COMPOSITIONS AND METHODS FOR REDUCING SCAR TISSUE FORMATION

Application 2429/KOLNP/2005 published 2006-09-15, filed 2005-11-30
The present invention describes the application of sirolimus and analogs of sirolimus to treat wound healing and reduce scar tissue formation. Also contemplated are non-sirolimus compounds believed to interact with the mTOR protein that have similar effects. Specifically, various medium are contemplated to create, for example, microparticles, foams, gels, sprays and bioadhesives that may be administered during surgical procedures involving either open or closed surgical site. Coating medical devices for long-term implantation is contemplated as one method of use of the above compositions (FIG. - nil)

Applicant

AFMEDICA INC
259 EAST MICHIGAN AVENUE SUITE 409 KALAMAZOO MI 49007 USA

Inventor

1. FISCHELL ROBERT E 2. FISCHELL TIM A 3. FISCHELL SARAH 4. WALDORF CLAYTON MACKENZIE

International Info

Classification: A61K
Publication Number: WO 04/110347 A2
Application Date: 2004-05-06

Priority Information

10/431,701 US 2003-05-07