CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR

Application IN/PCT/2000/00175/MUM published 2006-09-15, filed 2000-07-13
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by structural formula (I) and physiologically acceptable salts thereof. Drawing: 32 Total Pages: 197 (FIG.-NIL)

Applicant

1. MILLENNIUM PHARMACEUTICALS, INC., 2. KYOWA HAKKO KOGYO CO. LTD
1. 75 SIDNEY STREET, CAMBRIDGE, MASSACHUSETTS 02139, UNITED STATES OF AMERICA 2. 6-1 OHTEMACHI, 1-CHOME, CHIYODA-KU, TOKYO 100, JAPAN

Inventor

1. JAY R. LULY 2. YOSHISUKE NAKASATO 3. ETSUO OHSHIMA

International Info

Classification: C07D 491/044, A61K 31/445, 31/55, 31/495, CO7D 471/04, 495/04, 519/00, 313/12, 401/06, 405/06, 211/46
Publication Number: WO 99/37651

Priority Information

09/010, 320 U.S.A. 1998-01-21
09/148, 823 U.S.A. 1998-09-04